Vetenskap – Griffin Dental Academy

1. Assessment of Krillase chewing gum for the reduction of gingivitis and dental plaque.

Hellgren K.

J Clin Dent. 2009;20(3):99-102.

PMID: 19711611 [PubMed - indexed for MEDLINE]

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2. Use of gloves among dentists in Sweden–a 3-year follow-up study.

Hellgren K.

Swed Dent J. 1994;18(1-2):9-14.

PMID: 8052954 [PubMed - indexed for MEDLINE]

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3. Use of gloves among dentists in Sweden.

Hellgren K.

Swed Dent J. 1990;14(3):137-42.

PMID: 2255992 [PubMed - indexed for MEDLINE]

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4. Use of protective gloves for the purpose of infection control among dentists in the county of Malmöhus.

Hellgren K.

Tandlakartidningen. 1988 Oct 15;80(20):1107-12. Swedish. No abstract available.

PMID: 3270265 [PubMed - indexed for MEDLINE]

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5. Krill Enzymes (Krillase®) an Important Factor to Improve Oral Hygiene

By Kristian Hellgren

DOI: 10.5772/22056 978-953-51-0133-8,

Published: February 29, 2012 under CC BY 3.0 license. © The Author(s).

6. Journal of Periodontology

Abstract April 2013, Vol. 84, No. 4, Pages 513-519 , DOI 10.1902/jop.2012.100383

Soft-Tissue Alterations Following Exposure to Tooth-Whitening Agents

Rebekah N. Lucier,*† Olivier Etienne,* Susana Ferreira,† Jonathan A. Garlick,* Gerard Kugel,† and Christophe Egles*‡*Department of Oral and Maxillofacial Pathology, Division of Cancer Biology and Tissue Engineering, Tufts University School of Dental Medicine, Boston, MA.†Department of Research Administration, Tufts University School of Dental Medicine.‡Biomécanique et BioIngénierie, UMR-CNRS 7338, Université de Technologie de Compiègne, Compiègne, France.

Correspondence: Prof. Gerard Kugel, Tufts University School of Dental Medicine, Room 1015, 1 Kneeland Street, Boston, MA 02111. Phone: 617/636-0870; fax: 617/636-6511; e-mail:

Background: Tooth-whitening agents are widely used, either as self-application products or under the supervision of a dentist. These products may be associated with transient gross morphologic changes in oral soft tissues. However, their potential effects on human keratinocytes and fibroblasts in a stratified squamous epithelium have yet to be elucidated.

Methods: In this study, three-dimensional human tissue equivalents are exposed to varying concentrations of tooth-whitening agents for increasing time periods. Tissue alterations are investigated in terms of morphology, proliferation, apoptosis, and protein expression.

Results: All whitening agents tested altered tissue morphology, induced proliferation of basal keratinocytes, and caused apoptosis of cells in all epithelial strata. In addition, whitening agents induced alterations in the expression of cytokines that are linked to inflammation.

Conclusions: These results suggest that whitening agents may induce similar changes in vivo and that these products should be used for limited periods of time or under the supervision of a dental professional.

KEYWORDS: Bleaching agents, carbamide peroxide, epithelium, hydrogen peroxide, keratinocytes, toxicity

7. The plaque- and gingivitis inhibiting capacity of a commercially available essential oil product. A parallel, split-mouth, single blind, randomized, placebo-controlled clinical study.


Preus HR, et al.

Acta Odontol Scand, 2013, doi:10.3109/00016357.2013.782506.

8. Cellular responses to cobalt-chrome and CP titanium – an in vitro comparison of frameworks for implant-retained oral protheses


Swed Dent J 2011;35:177-186. Hjalmarsson et al.

9. Sinus bone formation and implant survival after sinusmembrane elevation and implant placement: a 1- to 6-year follow-up study

Clin.Oral.Impl.Res.2011;22 (10):p.1200-1212. Cricchio, G. et al

Kristian Hellgren profilbild

Kristian Hellgren

Leg. Tandläkare / Parodontolog


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